Summary. An Orphanet summary for this disease is currently under development. However, other data related to the disease are accessible from the Additional. Pittella JE, de Castro LP. Wernicke’s encephalopathy manifested as Korsakoff’s syndrome in a patient with promyelocytic leukemia. South Med. Wernicke encephalopathy (WE) is an acute neurological condition characterized by a clinical Diekfuss JA, De Larwelle J, McFadden SH.

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Almaraz Velarde 2F. Prevalence and predictors of postoperative thiamine deficiency after vertical sleeve gastrectomy. WE was first identified in by the German neurologist Carl Wernickealthough the link with encefaloopatia was not identified until the s.

There are no conclusive statistical studies, all figures are based on partial studies, and because of the ethical problems in conducting controlled trials are unlikely to be obtained in the future. To access free multiple choice questions on this topic, click here. An overview in health and wernidke PDF.

Wernicke encephalopathy – Wikipedia

If glucose is given, such as in hypoglycaemic alcoholics, thiamine must be given concurrently. Summary and related texts. Wernicke encephalopathy has classically been thought of as a disease solely of alcoholics, but it is also found in the chronically undernourished, and in recent werrnicke had been discovered post bariatric surgery. Autopsy series were performed in hospitals on the material available which is unlikely to be representative of the entire population.


Unusual early signs of Wernicke encephalopathy”. This criteria is challenged because all the cases he studied were alcoholics.

Case Reports in Oncology.

Lesions are usually symmetrical in the periventricular region, diencephalonthe midbrainhypothalamus, and cerebellar vermis. MRI is currently considered the most valuable imaging study available. Johnson JM, Fox V. Thiamine is a water-soluble B-complex vitamin that participates as a coenzyme in the oxidative decarboxylation of pyruvate and alfa-ketoglutarate and also in wernike pentose phosphate pathway.

StatPearls Publishing; Jan. Revue neurologique in French.

The classical triad is global confusional state, ocular abnormalities and ataxia. Wernicke encephalopathy after obesity surgery: Sechi G, Serra A.

Following this an immediate intravenous or intramuscular dose of thiamine should be administered [32] two or three times daily. A typical finding is the bilateral symmetrical T2 abnormal hyperintense signal affecting the periacqueductal gray matter, around the third ventricle and the medial thalamus and the mamillary bodies, 8 which can be found atrophic in a WE that has evolved for more than a week.


Thiamine administration is usually continued until clinical improvement ceases.

[Wernicke’s encephalopathy and Caine criteria. Report of six cases].

Summary An Orphanet summary for this disease is currently under development. External warming techniques are advised to prevent hypothermia. Korsakoff’s syndromecharacterised by memory impairment, confabulation, confusion and personality changes, has a strong and recognised link with WE.

Vitamin B 12 deficiency. Protein-energy malnutrition Kwashiorkor Marasmus Catabolysis.

Only one-third of patients will have all three of the typical symptoms, being the confusional state the most frequent one, followed by ataxia and ocular dysfunction. Brain and Nerve in Japanese. Nystagmus is the most common oculomotor dysfunction, and usually is evoked by horizontal gaze to both sides.

Pellagra Niacin deficiency B 6: Also, gait can worsen, and in many cases, patients are unable to walk. The documents contained in this web site are presented for information purposes only. A dietary consult should be done to assess the calorie ve and determine how to provide the food as well as thiamine.